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Sunday, September 12, 2021 - 1:00PM
at Highmark Stadium, Orchard Park, NY
CBS
Sunday, September 19, 2021 - 1:00PM
Buffalo Bills  35  vs
at Hard Rock Stadium, Miami Gardens, FL
FOX
Sunday, September 26, 2021 - 1:00PM
at Highmark Stadium, Orchard Park, NY
FOX - Chris Myers, Daryl Johnston,
Jen Hale

Sunday, October 3, 2021 - 1:00PM
at Highmark Stadium, Orchard Park, NY
CBS
Sunday, October 10, 2021 - 8:20PM
at GEHA Field at Arrowhead Stadium, Kansas City, MO
NBC
Monday, October 18, 2021 - 8:15PM
at Nissan Stadium, Nashville, TN
ESPN

Sunday, October 31, 2021 - 1:00PM
at Highmark Stadium, Orchard Park, NY
CBS
Sunday, November 7, 2021 - 1:00PM
at TIAA Bank Field, Jacksonville, FL
CBS
Sunday, November 14, 2021 - 1:00PM
at MetLife Stadium, East Rutherford, NJ
CBS

Sunday, November 21, 2021 - 1:00PM
at Highmark Stadium, Orchard Park, NY
CBS
Thursday, November 25, 2021 - 8:20PM
at Caesars Superdome, New Orleans, LA
NBC
Monday, December 6, 2021 - 8:15PM
at Highmark Stadium, Orchard Park, NY
ESPN

Sunday, December 12, 2021 - 4:25PM
at Raymond James Stadium, Tampa, FL
CBS
Sunday, December 19, 2021 - TBD
at Highmark Stadium, Orchard Park, NY
Sunday, December 26, 2021 - 1:00PM
at Gillette Stadium, Foxboro, MA
CBS

Sunday, January 2, 2022 - 1:00PM
at Highmark Stadium, Orchard Park, NY
FOX
Sunday, January 9, 2022 - 1:00PM
at Highmark Stadium, Orchard Park, NY
CBS