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Sunday, September 13, 2026 - 1:00 PM
(0-0) Buffalo Bills    vs
(0-0) Houston Texans  
at Reliant Stadium, Houston, TX
CBS
Head To Head for:
Buffalo vs Houston
Thursday, September 17, 2026 - 8:15PM
Thursday Night Football
(0-0) Detroit Lions    vs
(0-0) Buffalo Bills  
at Highmark Stadium, Orchard Park, NY
Amazon Prime
Head To Head for:
Detroit vs Buffalo
Sunday, September 27, 2026 - 1:00 PM
(0-0) Los Angeles Chargers    vs
(0-0) Buffalo Bills  
at Highmark Stadium, Orchard Park, NY
FOX
Head To Head for:
Los Angeles vs Buffalo
Sunday, October 4, 2026 - 1:00 PM
(0-0) New England Patriots    vs
(0-0) Buffalo Bills  
at Highmark Stadium, Orchard Park, NY
CBS
Head To Head for:
New England vs Buffalo
Monday, October 12, 2026 - 8:15 PM
Monday Night Football
(0-0) Buffalo Bills    vs
(0-0) Los Angeles Rams  
at SoFi Stadium, Inglewood, CA
ESPN
Head To Head for:
Buffalo vs Los Angeles
Sunday, October 18, 2026 - 4:25 PM
(0-0) Buffalo Bills    vs
(0-0) Las Vegas Raiders  
at Allegiant Stadium, Paradise, NV
CBS
Head To Head for:
Buffalo vs Las Vegas
Sunday, November 1, 2026 - 1:00 PM
(0-0) Baltimore Ravens    vs
(0-0) Buffalo Bills  
at Highmark Stadium, Orchard Park, NY
CBS
Head To Head for:
Baltimore vs Buffalo
Monday, November 9, 2026 - 8:15 PM
Monday Night Football
(0-0) Buffalo Bills    vs
(0-0) Minnesota Vikings  
at U.S. Bank Stadium, Minneapolis, MN
ESPN
Head To Head for:
Buffalo vs Minnesota
Sunday, November 15, 2026 - 1:00 PM
(0-0) Buffalo Bills    vs
(0-0) New York Jets  
at MetLife Stadium, East Rutherford, NJ
CBS
Head To Head for:
Buffalo vs New York
Sunday, November 22, 2026 - 1:00 PM
(0-0) Miami Dolphins    vs
(0-0) Buffalo Bills  
at Highmark Stadium, Orchard Park, NY
FOX
Head To Head for:
Miami vs Buffalo
Thursday, November 26, 2026 - 8:20PM
Thanksgiving Day Game
(0-0) Kansas City Chiefs    vs
(0-0) Buffalo Bills  
at Highmark Stadium, Orchard Park, NY
NBC
Head To Head for:
Kansas City vs Buffalo
Sunday, December 6, 2026 - 4:25 PM
(0-0) Buffalo Bills    vs
(0-0) New England Patriots  
at Gillette Stadium, Foxboro, MA
CBS
Head To Head for:
Buffalo vs New England
Sunday, December 13, 2026 - 8:20 PM
Sunday Night Football
(0-0) Buffalo Bills    vs
(0-0) Green Bay Packers  
at Lambeau Field, Green Bay, WI
NBC
Head To Head for:
Buffalo vs Green Bay
Saturday, December 19, 2026 - 8:20 PM
Saturday Football Game
(0-0) Chicago Bears    vs
(0-0) Buffalo Bills  
at Highmark Stadium, Orchard Park, NY
CBS
Head To Head for:
Chicago vs Buffalo
Friday, December 25, 2026 - 4:30 PM
Christmas Day Game
(0-0) Buffalo Bills    vs
(0-0) Denver Broncos  
at Empower Field at Mile High, Denver, CO
Netflix
Head To Head for:
Buffalo vs Denver
Sunday, January 3, 2027 - 1:00 PM
(0-0) Buffalo Bills    vs
(0-0) Miami Dolphins  
at Hard Rock Stadium, Miami Gardens, FL
CBS
Head To Head for:
Buffalo vs Miami
Sunday, January 10, 2027 - TBD
(0-0) New York Jets    vs
(0-0) Buffalo Bills  
at Highmark Stadium, Orchard Park, NY
Head To Head for:
New York vs Buffalo