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Sunday, September 12, 2021 - 1:00PM
at Ford Field, Detroit, MI
FOX - Kevin Kugler, Mark Sanchez,
Laura Okmin
First game for Detroit head coach Dan Campbell
Monday, September 20, 2021 - 8:15PM
Detroit Lions  17  vs
at Lambeau Field, Green Bay, WI
ESPN - Steve Levy, Brian Griese, Louis Riddick,
Lisa Salters
Sunday, September 26, 2021 - 1:00PM
at Ford Field, Detroit, MI
CBS - Greg Gumbel, Adam Archuleta,
A.J. Ross
BAL K Justin Tucker kicks NFL record 66 yd GW FG on last play of the game.

Sunday, October 3, 2021 - 1:00PM
Detroit Lions  14  vs
at Soldier Field, Chicago, IL
FOX - Gus Johnson, Aqib Talib,
Megan Olivi
Sunday, October 10, 2021 - 1:00PM
Detroit Lions  17  vs
at U.S. Bank Stadium, Minneapolis, MN
FOX
U.S. Bank Stadium Legacy Gate doors open.
MINN K Greg Joseph kicks 54 yard GW FG on last play of the game.
Sunday, October 17, 2021 - 1:00PM
at Ford Field, Detroit, MI
FOX

Sunday, October 24, 2021 - 4:05PM
at SoFi Stadium, Inglewood, CA
FOX
Sunday, October 31, 2021 - 1:00PM
at Ford Field, Detroit, MI
FOX
Sunday, November 14, 2021 - 1:00PM
at Heinz Field, Pittsburgh, PA
FOX

Sunday, November 21, 2021 - 1:00PM
at FirstEnergy Stadium, Cleveland, OH
FOX
Thursday, November 25, 2021 - 12:30PM
at Ford Field, Detroit, MI
FOX
Sunday, December 5, 2021 - 1:00PM
at Ford Field, Detroit, MI
CBS

Sunday, December 12, 2021 - 4:05PM
at Empower Field at Mile High, Denver, CO
FOX
Sunday, December 19, 2021 - 1:00PM
at Ford Field, Detroit, MI
FOX
Sunday, December 26, 2021 - 1:00PM
at Mercedes-Benz Stadium, Atlanta, GA
FOX

Sunday, January 2, 2022 - 4:25PM
at Lumen Field, Seattle, WA
FOX
Sunday, January 9, 2022 - 1:00PM
at Ford Field, Detroit, MI
FOX