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Thursday, September 9, 2021 - 8:20PM
at Raymond James Stadium, Tampa, FL
NBC - Al Michaels, Cris Collinsworth,
Michele Tafoya
Tampa Bay QB Tom Brady makes his 300th NFL start
Sunday, September 12, 2021 - 1:00PM
at Nissan Stadium, Nashville, TN
CBS - Tom McCarthy, Aaron Taylor
Sunday, September 12, 2021 - 1:00PM
at NRG Stadium, Houston, TX
CBS - Greg Gumbel, Adam Archuleta,
A.J. Ross
First game for Jacksonville head coach Urban Meyer
First game for Houston head coach David Culley

Sunday, September 12, 2021 - 1:00PM
at FedEx Field, Landover, MD
CBS - Spero Dedes, Jay Feely
First game for Los Angeles head coach Brandon Staley
Sunday, September 12, 2021 - 1:00PM
at Paul Brown Stadium, Cincinnati, OH
FOX - Chris Myers, Daryl Johnston,
Jen Hale
Sunday, September 12, 2021 - 1:00PM
at Bank of America Stadium, Charlotte, NC
CBS - Andrew Catalon, Tiki Barber,
Sherree Burress
First game for New York head coach Robert Saleh

Sunday, September 12, 2021 - 1:00PM
at Mercedes-Benz Stadium, Atlanta, GA
FOX - Kevin Burkhardt, Greg Olsen,
Pam Oliver
Mercedes-Benz Stadium roof open.
First game for Atlanta head coach Arthur Smith
First game for Philadelphia head coach Nick Sirianni
Sunday, September 12, 2021 - 1:00PM
at Highmark Stadium, Orchard Park, NY
CBS - Ian Eagle, Charles Davis,
Evan Washburn
Sunday, September 12, 2021 - 1:00PM
at Lucas Oil Stadium, Indianapolis, IN
FOX - Kenny Albert, Jonathan Vilma,
Sara Walsh

Sunday, September 12, 2021 - 1:00PM
at Ford Field, Detroit, MI
FOX - Kevin Kugler, Mark Sanchez,
Laura Okmin
First game for Detroit head coach Dan Campbell
Sunday, September 12, 2021 - 4:25PM
at GEHA Field at Arrowhead Stadium, Kansas City, MO
CBS - Jim Nantz, Tony Romo,
Tracy Wolfson
Sunday, September 12, 2021 - 4:25PM
at MetLife Stadium, East Rutherford, NJ
FOX - Adam Amin, Mark Schlereth,
Shannon Spake

Sunday, September 12, 2021 - 4:25PM
at TIAA Bank Field, Jacksonville, FL
FOX - Joe Buck, Troy Aikman,
Erin Andrews, Tom Rinaldi
Game moved due to effects from Hurricane Ida.
Sunday, September 12, 2021 - 4:25PM
at Gillette Stadium, Foxboro, MA
CBS - Kevin Harlan, Trent Green,
Melanie Collins
Sunday, September 12, 2021 - 8:20PM
at SoFi Stadium, Inglewood, CA
NBC - Al Michaels, Cris Collinsworth,
Michele Tafoya

Monday, September 13, 2021 - 8:15PM
at Allegiant Stadium, Paradise, NV
ESPN/ABC - Steve Levy, Brian Griese, Louis Riddick,
Lisa Salters