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Thursday, September 30, 2021 - 8:20PM
at Paul Brown Stadium, Cincinnati, OH
NFL Network - Joe Buck, Troy Aikman,
Kristina Pink, Erin Andrews
CIN K Evan McPherson kicks 35 yd FG on last play of the game.
Sunday, October 3, 2021 - 1:00PM
at AT&T Stadium, Arlington, TX
FOX - Kevin Burkhardt, Greg Olsen,
Pam Oliver
CAR QB Sam Darnold becomes the first QB to have 5 rushing TDs in his teams first 4 games.
Sunday, October 3, 2021 - 1:00PM
at U.S. Bank Stadium, Minneapolis, MN
CBS - Kevin Harlan, Trent Green,
Melanie Collins
U.S. Bank Stadium Legacy Gate doors open.

Sunday, October 3, 2021 - 1:00PM
Detroit Lions  14  vs
at Soldier Field, Chicago, IL
FOX - Gus Johnson, Aqib Talib,
Megan Olivi
Sunday, October 3, 2021 - 1:00PM
at Highmark Stadium, Orchard Park, NY
CBS - Beth Mowins, Tiki Barber
Sunday, October 3, 2021 - 1:00PM
at Hard Rock Stadium, Miami Gardens, FL
CBS - Spero Dedes, Jay Feely

Sunday, October 3, 2021 - 1:00PM
at Lincoln Financial Field, Philadelphia, PA
CBS - Ian Eagle, Charles Davis,
Evan Washburn
4th game in NFL history without a punt by either team.
Sunday, October 3, 2021 - 1:00PM
at Caesars Superdome, New Orleans, LA
FOX - Kenny Albert, Jonathan Vilma,
Sara Walsh
Sunday, October 3, 2021 - 1:00PM
New York Jets  27  OT
at MetLife Stadium, East Rutherford, NJ
CBS - Greg Gumbel, Adam Archuleta,
A.J. Ross

Sunday, October 3, 2021 - 1:00PM
at Mercedes-Benz Stadium, Atlanta, GA
FOX - Kevin Kugler, Mark Sanchez,
Laura Okmin
Sunday, October 3, 2021 - 4:05PM
at SoFi Stadium, Inglewood, CA
FOX - Chris Myers, Daryl Johnston,
Jen Hale
Sunday, October 3, 2021 - 4:05PM
at Levis Stadium, Santa Clara, CA
FOX - Adam Amin, Mark Schlereth,
Shannon Spake

Sunday, October 3, 2021 - 4:25PM
at Empower Field at Mile High, Denver, CO
CBS - Andrew Catalon, James Lofton,
Amanda Balionis
Sunday, October 3, 2021 - 4:25PM
at Lambeau Field, Green Bay, WI
CBS - Jim Nantz, Tony Romo,
Tracy Wolfson
Sunday, October 3, 2021 - 8:20PM
at Gillette Stadium, Foxboro, MA
NBC - Al Michaels, Cris Collinsworth,
Michele Tafoya
TB QB Tom Brady passes Drew Brees for most career passing yards.

Monday, October 4, 2021 - 8:50PM
at SoFi Stadium, Inglewood, CA
ESPN - Steve Levy, Brian Griese, Louis Riddick,
Lisa Salters
Game delayed 35 minutes from 8:15 PM original kickoff due to lightning.
LAC QB Justin Herbert becomes 1st QB in NFL history to complete 500 passes before his 20th start.